Objective: To explore the effects of curcumin on retinal neovascularization in oxygen-induced retinopathy (OIR) model and the mechanism in this process.

目的：探讨姜黄素对高氧诱导的视网膜病变(oir)动物模型视网膜新生血管的作用及其作用机制。

Conclusion: PDGF expression is obviously increased in OIR patients nimodipine can prevent OIR and it can inhibit the expression of PDGF to a certain extent.

结论：PDGF在OIR组织中表达明显增加，而钙通道拮抗剂尼莫地平可抑制OIR的发生，并在某种程度上抑制PDGF的表达。