Charlie is a regular pain in the ass.

查理是个老让人生厌的家伙.

You can also sand the anodizing off, but I don't recommend it because its a pain in the ass.

您也可以在沙阳极氧化了，但我不推荐，因为它的一个痛苦的屁股。

It’s a pain in the ass to find one, but there is some form of exercise that you will love.

寻找到一个你自己钟爱的锻炼方式是一个十分痛苦的过程。

In scientific terms, teenagers can be a pain in the ass. But they are quite possibly the most fully, crucially adaptive human beings around.

从科学角度来看，青少年可能是个讨厌鬼，但他们很可能就是最出色最彻底的环境适应者。