Objective: To study the effect of Jiangu granules (JGG) on osteoporosis.

目的：研究健骨冲剂防治骨质疏松的作用。

To explore the therapeutic effect and mechanism of Jiangu granule (JGG) on postmenopausal osteoporosis.

目的探索健骨冲剂对绝经后骨质疏松症疗效的作用机制。

Conclusion: JGG could prevent and cure osteoporosis induced by the decrease of estradiol, but its mechanism of action might not rely on ameliorating the function of ovary.

结论：表明健骨冲剂能防治因雌二醇下降所致的骨质疏松症，但其作用机制不一定通过提高卵巢功能来实现。

Methods differential display reverse transcription PCR (DDRT-PCR) was used to detect the differentially expressed genes in bone tissues associated with therapeutic effect of JGG.

方法采用差异显示反转录- P CR (DDRT - PCR)方法，寻找骨组织内与健骨冲剂疗效相关的有差异表达的基因。