Atypical ductular proliferation is related to hepatocyte regeneration and small hepatocyte-like cells may be intermediate transient cells between hepatic oval cells and mature hepatocyte.

小型肝细胞样细胞可能是肝卵圆细胞与成熟肝细胞之间的中间过渡细胞。

Both HGF and FGF4 can induce umbilical cord blood MNC to differentiate into hepatocyte-like cells singly or coordinately.

FGF4均能在体外诱导人脐血MNC分化为肝细胞样细胞，且二者在一定程度上有联合作用。

OBJECTIVE:To conclude and analyze the methods, mechanism and existing problems of MSCs differentiation into hepatocyte-like cells.

目的：总结和分析间充质干细胞向肝样细胞诱导分化的方法、机制以及存在的问题。

OBJECTIVE: To conclude and analyze the methods, mechanism and existing problems of MSCs differentiation into hepatocyte-like cells.

目的：总结和分析间充质干细胞向肝样细胞诱导分化的方法、机制以及存在的问题。

Results Hepatectomized rat serum and HGF were demonstrated to have the effect of inducing transdifferentiation of ABMSCs into hepatocyte-like cells in vitro.

将分化细胞经尾静脉输入同系大鼠，观察输注细胞在肝、脾内的生长情况。