Objective To evaluate the antidepressant effect of Ganmai DazaoDecoction.

目的探讨甘麦大枣合百合地黄汤的抗抑郁作用.

Method The mouse model of forced-swimming was established to evaluate the antidepressant effect of KP.

方法采用小鼠强迫性游泳模型，评价开心散的抗抑郁作用；

MethodsUsing the forced swimming test and tail suspension test in mice, the antidepressant effect of hehuanhua was observed.

方法采用小鼠强迫游泳实验和小鼠悬尾实验研究合欢花水提物的抗抑郁作用。

Results YJ-E could decrease the duration of immobility in the TST and FST and showed potent antidepressant effect, but YJ-W has no obvious effects.

结果越鞠丸醇提物能不同程度地缩短小鼠悬尾不动时间和小鼠强迫游泳不动时间，具有较强的抗抑郁作用；