To establish the model of bowel dysfunction after acute shigella flexneri infection by imitating the natural course of human postinfectious irritable bowel syndrome.

目的：模仿人类感染后肠易激综合征的自然发病过程，建立急性细菌感染后肠功能紊乱的大鼠模型。

Methods Rabbit models of intestinal invasion induced by Shigella flexneri was established by directly inoculating the bacterium in the colon after cecum bypass operation.

方法兔盲肠分流术后直接结肠内接种，制作菌痢兔模型。