In spite of intense research in the field of epilepsy, a key question remains unanswered: what are the earliest cellular events leading to the initiation of a focal seizure?

尽管以往对癫痫进行了热烈的研究，但仍有一个关键问题没有得到解答：导致癫痫局灶性癫痫发作启动最早的细胞活动在是怎样的？