Briefly investigated the effect of different active component on synthesizing pyrrolidine.

简要考察了不同活性组分对合成四氢吡咯的影响。

CONCLUSION Pyrrolidine derivatives exhibited potent neuraminidase inhibitory activities, and is worth of further investigation.

结论吡咯烷类化合物对神经氨酸酶有较高的抑制活性，值得进一步研究。

Li says the ants were able to cross the cleaned silk but were unable to cross in the two cases where pyrrolidine alkaloid was present.

李说：“蚂蚁能够爬过干净的蜘蛛丝，但不能爬过存有生物碱的蜘蛛丝。”

OBJECTIVE To synthesize a series of novel pyrrolidine derivatives as neuraminidase inhibitors and test their inhibitory activities against neuraminidase.

目的合成新型吡咯烷类神经氨酸酶抑制剂，并测定其抑制神经氨酸酶的活性。

METHODS a series of pyrrolidine derivatives were synthesized from L-hydroxyproline, and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening.

方法以L -羟脯氨酸为原料，合成一系列神经氨酸酶抑制剂，并用高通量活性筛选方法检测其对神经氨酸酶的抑制活性。

The reactions are performed more conveniently in two phase systems consisted of alcoholic solvents and K_2CO_3, and may be adapted for the synthesis of pyrrolidine and oxazolidine derivatives.

这些反应在质子性醇溶剂与K_2CO_3组成的两相体系中进行更为方便，可用于吡咯烷及恶唑烷衍生物的合成。