AIM: to investigate the mechanisms of augmenter of liver regeneration (ALR) in promoting damaged hepatocyte proliferation.

目的：探讨肝细胞增殖因子(alr)促进受损肝细胞增殖的可能机制。

Objective To observe the effects of recombinant augmenter of liver regeneration (ALR) on the proliferation of hepatic stellate cell line IG12 and ECM synthesis.

目的观察重组大鼠肝再生增强因子(alr)对肝星状细胞株ig12增殖及细胞外基质合成的影响，探讨其抗肝纤维化作用的可能机制。

Objective To select an optimal combined set of carrier, introducing route and dose of recombinant plasmid of augmenter of liver regeneration (ALR) for ALR gene therapy.

目的筛选肝再生增强因子重组质粒基因治疗时较优的载体、途径和剂量及三者的最佳组合。