He had an ill-favored look.

他看起来真是个丑八怪。

This young girl was quite cute. Actually, now that genetic engineering was so advanced, trying to find a person of ill-favored appearance was far more difficult than going into space.

这位少女长得相当可爱，其实在基因工程发达的今天，想找一个长相不佳的丑人，只怕比登天还难。