He was twenty-eight, a tall, well-built man, who did not seem, however, to think his appear-ance was very important.

他28岁，身材高大魁梧，不过他好像并不认为自己的外表很重要。

In short, this guideline suggests that compelling problems or issues of great import-ance should drive the research questions asked and the means taken to answer them.

简而言之，这个准则建议，对重大问题或具有重要性的事情，应该引导研究去提出问题并找到相应的办法解决。