You are responsible for completing your work.

你有责任完成你的工作。

Henceforth, you are responsible for this project.

从此以后，你将负责这个项目。

As a self-employed person, you are responsible for your own taxes.

作为自雇者，你需要自己负责缴税。

As the team leader, you are responsible for ensuring everything goes smoothly.

作为团队领导，你有责任确保一切顺利进行。

You are responsible for washing out your own lab equipment and putting it away.

你有责任把自己的实验室设备洗干净并放好。

Now you are responsible for everything.

现在你要为所有事负责。

You are responsible for third kid………………….

（肚子里的）第三个孩子是你的责任……。

You are responsible for your own grief process.

你是你自己的悲痛过程负责。

You are responsible for keeping the files in order.

你负责整理文件.

You are responsible to open the Student Admin Office.

管理员应负责开学生值班室的门。