The different forms of tubulin are very similar, and they can co-polymerize into microtubules reversibly.

这些不同类型的微管蛋白非常相似，并且它们能可逆性聚合成微管。

It possesses a unique mechanism of action as promoters of tubulin aseembly and inhibitors of microtubule disassembly.

它的作用机理独特，通过诱导和促进微管蛋白聚合形成稳定结构，从而抑制微管解聚。

Target compounds 4 and 5 were tested in a tubulin assembly assay, and in an in vitro cytotoxicity assay(KB cell line).

将目标化合物进行了抗肿瘤体外试验和微管聚合试验。

ABT-751 is an orally-active anticancer agent acting through the binding with the colchicine binding site on the tubulin.

ABT - 751是透过和微小管上的秋水仙素碱键结位置键结产生作用的口服有活性的抗癌化合物。

Another reported Chromene derivatives can strongly inhibit tubulin aggregation and play an efficient role against cancer.

另外有报道色烯类衍生物可以强烈的抑制微管蛋白聚合，从而发挥抗癌作用。

The dynamic changes, of MT included: MT disaggregated into tubulin, and a flat-shaped microtubules-network was reorganized.

微管的动态变化包括解聚成微管蛋白及重组成扁平形微管网。

Conclusion 5f inhibits tubulin polymerization and depolymerization, and leads to cell cycle arrested, and possibly induces apoptosis.

结论5f能抑制体外微管蛋白聚合，从而可能是影响细胞的细胞周期及诱导凋亡途径之一。

Results 5f decreased the Absorption values of the reaction system. and markedly inhibited not only tubulin polymerization but also tubulin depolymerization.

结果5f能抑制反应体系吸光值升高，提示它对微管蛋白聚合具有抑制作用并能抑制其解聚。

The result suggested that TBZ may induce aneuploidy by the pathway of tubulin polymerization inhibition which is able to lead to chromosomal malsegregation.

研究表明，TBZ可能通过抑制微管蛋白聚合来影响染色体正常分离，诱发非整倍体。

We extracted rabbit brain tubulin, and then detected by turbidimetric credit made the active ingredient of mahonia the impact of polymerization - depolymerization of tubulin.

提取兔脑微管蛋白采用比浊发检测功劳木活性成分对微管蛋白聚合-解聚的影响。

Rabbit brain in vitro tubulin polymerization-depolymerization showed that jatrorrhizine and berberine can inhibit tubulin polymerization, and jatrorrhizine are stronger than that of berberine.

体外兔脑微管蛋白聚合-解聚分析表明，药根碱和小檗碱均能抑制微管蛋白的聚合，且药根碱作用强于小檗碱。